Websep 23, 2021 · in many cases, you can treat a spider bite at home. You may experience mild symptoms for 1 to 2 days. Bites that itch or are infected may require more treatment. Webjul 30, 2021 · spider bites are usually harmless, and spiders don't usually bite unless threatened. Spider bites can cause redness, pain and swelling, or you might not notice. Websigns and symptoms of spider bites. Signs and symptoms of spider bites depend on the amount of venom injected and the person’s sensitivity to the venom.