Webaug 18, 2024 · lip twitching, also known as myokymia, refers to involuntary, repetitive muscle contractions in the lip area. These twitches can range from barely noticeable. Weblip twitching, also named lip fasciculations, is an anomalous irregular contraction of the muscle fibers in the area surrounding the lips. Lip twitching is involuntary, and it can also.