Webhow to take it. Take sertraline once a day. You can take it with or without food. You can choose to take sertraline at any time, as long as you stick to the same time every day. Weboct 1, 2024 · take this medicine on an empty stomach. Do not take this medicine with food or right after a meal because it may not work as well. Do not take this medicine if you. Weboct 1, 2024 · if you take them together or do not wait 14 days, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, a sudden high body. Weboct 1, 2024 · follow the instructions carefully. Ask your doctor if you have any questions. The tablets may be taken with or without food. If you are taking the oral liquid, use the. Websertraline (zoloft) is a very common prescription medication that can help treat depression and other mental health conditions. Talk to your healthcare provider about any concerns. Webjul 13, 2021 · gastrointestinal side effects (ses) are frequently observed in patients with major depressive disorder (mdd) while taking antidepressants and may lead to.